Next-Generation Monitoring Systems for Personalized Perioperative Care
Marek Antoniou, Diego Marques, Henrik SolbergPerioperative monitoring is shifting from intermittent, population-thresholded measurements toward continuous, patient-specific signals that machine-learning models increasingly try to forecast rather than merely display. This review examines four converging strands of that shift: closed-loop anesthesia delivery built on refined depth-of-anesthesia measurement, continuous noninvasive hemodynamic monitoring and the predictive hypotension algorithms trained on its waveforms, wearable and wireless sensors extending vigilance onto the surgical ward, and the multimodal data-fusion efforts attempting to unify these separate streams into a single patient model. Closed-loop hypnotic titration achieves tighter control of anesthetic depth than manual dosing in several trials, continuous noninvasive pressure monitoring now performs acceptably against invasive references in stable patients, and wearable ward sensors are feasible and well tolerated, but hypotension-prediction algorithms have drawn methodological scrutiny over feature entanglement, and outcome-level evidence across all four domains remains comparatively immature. Persistent barriers are as much organizational as technical: alarm fatigue, uneven workflow integration, vendor interoperability, and unequal access to the informatics infrastructure that multimodal integration requires. We conclude that realizing genuinely personalized perioperative monitoring will depend on prospective outcome trials and organizational readiness at least as much as on further algorithmic refinement.