Outline
DOI: 10.1039/d6ra05385h ISSN: 2046-2069
New sulfonamide derivatives as HDAC inhibitors and apoptosis inducers: design, synthesis, in silico study and anticancer evaluation
Omkulthom Al kamaly, Esmail M. El-Fakharany, Yousra A. El-Maradny, Lama A. Alshabani, Aisha Alsfouk, Abdallah E. AbdallahCompound 10 inhibited HDAC2 with correct binding mode, induced apoptosis and elevated apoptosis markers in treated MCF-7 cells.
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