NEPHROTOXICITY OF MEDICINES AND ACUTE KIDNEY INJURY. REVIEW OF LITERATURE

Some medicines prescribed in the framework of a comprehensive treatment of various diseases cause nephrotoxicity in patients undergoing treatment in a hospital and resuscitation and intensive care unit. In 14–27% cases of nephrotoxicity development an acute kidney injury was observed. Use of biomarkers allows early detection of initial signs of nephrotoxicity and acute kidney injury. Reasonable approach to prescription of medicines, assessment of risk factors and abandoning of polypharmacy are the fundamentals of prevention of nephrotoxicity development.