Neonatal Salmonella typhi sepsis with meningitis: A rare case report

ABSTRACT

Neonatal sepsis due to Salmonella typhi is rare but can lead to life-threatening complications. The clinical manifestations are generally similar to those of sepsis caused by other Gram-negative pathogens in newborns. The exact route of transmission remains unclear, with both vertical and horizontal spread proposed. Diagnosis is confirmed by isolating the organism through blood cultures. Management primarily involves supportive care and intravenous antibiotic therapy. We present the case of a 21-day-old neonate admitted to our neonatal intensive care unit with clinical features of sepsis, which was subsequently confirmed to be S. typhi sepsis with meningitis.