DOI: 10.59578/jmsni.2026.17.1.7-10 ISSN: 2733-8290
Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease Presenting as Cortical Encephalitis in A Patient with Crohn’s Disease Receiving Anti-Tumor Necrosis Factor Therapy
Joo Yeon Lee, Jin Myoung Seok, Jee Hyun KimA 28-year-old man with Crohn’s disease receiving infliximab developed focal motor seizures with unilateral cortical hyperintensity on brain magnetic resonance imaging and serum myelin oligodendrocyte glycoprotein (MOG)-immunoglobulin G positivity, consistent with MOG antibody-associated disease (MOGAD) presenting as cortical encephalitis. His symptoms improved after corticosteroid therapy. MOGAD should be considered in patients receiving anti-tumor necrosis factor therapy who develop new-onset cortical manifestations.