DOI: 10.1093/ced/llag352 ISSN: 0307-6938
Mosaic HRAS variant presenting with painful asymmetrical palmoplantar calluses: a case report and literature review
Jonathan Chan, Kapila Batta, John A G Buchanan, Edel A O’TooleCostello syndrome is a multi-system disorder most commonly caused by the HRAS p.G12S variant, with many possible dermatological features. We present a mosaic presentation of this variant. The case highlights the importance of considering HRAS variants as a cause of painful asymmetrical palmoplantar calluses