DOI: 10.4103/jasi.jasi_1_26 ISSN: 0003-2778

Morphometric Study of the Frontal Horn of Lateral Ventricles of the Human Brain using Computed Tomography and Its Clinical Significance in the Central Gujarat Region

Vaibhavi Dipakbhai Bhatti, Mayur Bhagavanjibhai Baraiya, Pratik Maheshbhai Parekh

Introduction:

Morphometric analysis of the cerebral ventricular system is essential for distinguishing normal age-related changes from pathological conditions such as hydrocephalus or cortical atrophy. Since ventricular dimensions vary across populations, establishing region-specific normative data is crucial for accurate clinical diagnosis and surgical planning.

Materials and Methods:

A hospital-based cross-sectional study was conducted in the department of anatomy at a tertiary care teaching hospital in Western India. Computed tomography (CT) scans of 200 subjects (100 males and 100 females) aged 18–80 years were analyzed after obtaining informed consent. Participants were stratified into five age groups. Standardized morphometric measurements of the frontal horns of the lateral ventricles were performed on axial CT images. Statistical tests included Student’s t -test for gender comparisons, paired t -test for sidewise differences, and one-way analysis of variance for age-related variations. Reliability was assessed using intraclass correlation coefficients.

Results:

The left frontal horn was consistently longer than the right in both genders ( P < 0.001). Males exhibited statistically significant but modestly larger ventricular dimensions compared to females. Age-stratified analysis revealed progressive ventricular expansion across groups, with significant differences observed in older participants. These findings highlight both physiological asymmetry and demographic influences on ventricular morphology.

Conclusion:

This study establishes baseline morphometric data for the frontal horns of the lateral ventricles in the central Gujarat population. These normative values provide valuable reference points for neuroanatomists, neuroradiologists, and neurosurgeons, aiding in the differentiation of normal anatomical variants from pathological enlargement. Age-related changes should be interpreted cautiously, and further multicentric studies are recommended to validate these findings.