DOI: 10.1039/d6sc03784d ISSN: 2041-6520

Modular synthesis of α-tertiary amino acids from C–H feedstocks

Mengfei Xu, Emma Yang, Vy M. Dong

Visible-light Pd catalysis enables access to α-tertiary unnatural amino acids (UAAs) and their conversion into prolines, azepanes, pyrrolizidines, and other cyclic motifs from simple C–H feedstocks, 1,3-butadiene, and amidomalonate esters.

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