DOI: 10.1136/bmjhci-2025-101954 ISSN: 2632-1009

Missing infrastructure for real-world predictive AI impact

Benjamin I Perry, Ben Hammond, Dominic Oliver, Ashley Mushambi, Carina Andrews, Niels Peek, Ben Van Calster, Laure Wynants, Annabel E L Walsh, Joseph E Alderman, Shuqing Si, Alastair K Denniston, Simon J Griffin, Joie Ensor

Health systems are under increasing pressure as chronic disease becomes the dominant burden of care. Addressing this requires earlier detection and prevention, and predictive artificial intelligence (AI) tools are a demonstrable means of targeting interventions more effectively. Despite extensive research activity and substantial public funding, few predictive AI tools are translated effectively into routine care. We argue that the primary translational barrier is now organisational rather than solely methodological: without defined institutional ownership and long-term stewardship, including to support obtaining and maintaining regulatory certification and navigating governance structures, predictive AI tools cannot progress beyond print. Three interdependent recommendations are proposed to address this problem.

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