DOI: 10.1093/ofid/ofae684 ISSN: 2328-8957
Missed and Delayed Diagnoses of Acute Human Immunodeficiency Virus (HIV) Infection in a Southern Opt-Out HIV Testing Environment Without Reflex HIV RNA Testing
Sarah F Gruber, Eli P Wilber, Brittany Smith, Paulina A Rebolledo, Jonathan A Colasanti, Rishika Iytha, Megan Schwinne, Chad Robichaux, Meredith H LoraAbstract
Prompt confirmation of human immunodeficiency virus (HIV) is critical. We examined 10 years of discordant results without reflex HIV RNA. Of patients with acute HIV infection, 43.9% (95% confidence interval, 36.2%–52.0%) had confirmation delays >30 days or were never confirmed, indicating a need for reflex RNA to facilitate diagnosis.