DOI: 10.3390/brainsci16101040 ISSN: 2076-3425
Migraine in Real-World Clinical Practice: Patient Burden, Healthcare Utilization and Unmet Needs—A Cross-Sectional Analysis of the I-GRAINE Study
Piero Barbanti, Jesuély Spieckert de Souza, Giulia Fiorentini, Francesca Pistoia, Cecilia Camarda, Alberto Doretti, Gabriella Egeo, Florindo d’Onofrio, Cinzia Aurilia, Marco Bartolini, Simone Braca, Antonio Carnevale, Rosario Grugno, Massimo Autunno, Maurizio Zucco, Marco Russo, Simone Quintana, Stefano Caproni, Alfonsina Di Summa, Paola Scatena, Massimo Filippi, Monica Laura Bandettini Di Poggio, Cinzia Finocchi, Alessandra Cherchi, Paolo Solla, Riccardo Altavilla, Barbara Petolicchio, Annalisa Gai, Mattia Sansone, Rossana Terlizzi, Francesco Bono, Gennaro Saporito, Stefano Messina, Elisabetta Iannaccone, Roberto De Simone, Valentina Favoni, Martina Guarinoni, Giovanna Viticchi, Domenico Cosenza, Ludovica Ferraù, Laura Di Clemente, Prabha Cristina Ranchicchio, Steno Rinalduzzi, Ilaria Cetta, Sara Cazzulo, Francesco Tazza, Tommaso Ercoli, Carla Zanferrari, Francesca Gragnani, Pietro Antonio Bruno, Renata Rao, Fabio Valguarnera, Maria Albanese, Licia Grazzi, Fabrizio Vernieri, Alfonso Coppola, Carlo Colosimo, Francesca Cortese, Fabrizio Di Stani, Frederico Friedrich, Vanise Grassi, Carlo Tomino, Stefano Bonassi, Annamaria Porreca, Paola Torelli, Sabina Cevoli,What are the main findings?Migraine care in Italy is characterized by a mismatch between healthcare resource utilization and clinical needs, with limited primary-care involvement, repeated specialist consultations, and healthcare nomadism.Healthcare resource utilization is substantial, including extensive diagnostic testing—predominantly brain imaging—as well as emergency department visits, detoxification cycles, and repeated access to headache centers.