DOI: 10.1039/d4lc00290c ISSN: 1473-0197

Microfluidic synthesis of hemin@ZIF-8 nanozyme with applications in cellular reactive oxygen species detection and anticancer drug screening

Yanping Wang, Shujun Feng, Xuyuan Wang, Chungui Tao, Yuta Liu, Yanyi Wang, Yanfeng Gao, Jinsong Zhao, Yujun Song

A microfluidic chip featuring zigzag and spiral channels with sudden expansion structures was designed for enhanced reactant mixing to synthesize peroxidase-like hemin@ZIF-8 nanozyme, enabling sensitive ROS detection.

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