Microcomputed Tomography-derived Finite Element Evaluation of Osseointegration Dynamics and Bone–Implant Bond Strength
Abdulrahman Mohammed Alduhailan, Abhijit Bajirao Jadhav, Veeriah Chowdary Jasthi, Girish Meravanige, Sreeharsha Nagaraja, Barsha Tripathy, Ahmad Saib JameelAbstract
Introduction:
The integration of microcomputed tomography (microCT) with finite element modeling (FEM) offers a powerful nondestructive approach for evaluating bone–implant interactions. This research was done to investigate osseointegration dynamics and bone–implant bond strength using microCT-derived finite element analysis (FEA).
Materials and Methods:
A total of 264 subjects were divided equally into control and experimental groups. High-resolution microCT imaging was performed to quantify peri-implant bone morphology, followed by specimen-specific FEM using validated computational platforms. Morphometric parameters including bone volume fraction, trabecular thickness, and bone–implant contact (BIC) were analyzed alongside biomechanical indices such as von Mises stress, strain distribution, and interfacial micromotion. Statistical analysis was conducted using SPSS and GraphPad Prism, with significance set at
Results:
The experimental group demonstrated significantly improved peri-implant bone architecture, with higher bone volume fraction and increased BIC compared to controls (
Conclusion:
The integration of microCT imaging with FEM provides a robust, nondestructive, and highly sensitive framework for evaluating osseointegration dynamics. Microstructural bone parameters are strongly predictive of biomechanical implant stability.