DOI: 10.47493/abantmedj.1283992 ISSN: 1305-4392

Melphalan Tedavisi Alan Otolog Kök Hücre Transplantasyonu Olan Hastalarda Mukozitten Korunmada Oral Buz Uygulamasının Etkisi: Randomize Kontrollü Bir Çalışma

Solmaz ZEYBEKÇİ, Özlem UĞUR, Gülay ŞAHİN, Gülşah BEDEZ, Derya ÜNSEL, Tuba ÜLGEN, Boran YAVUZ, Ahmet ŞEYHANLI, İnci ALACACIOĞLU, Hayri ÖZSAN
  • General Earth and Planetary Sciences
  • General Engineering
  • General Environmental Science
Objective: To examine the effect of oral cryotherapy in the prevention of mucositis in patients with autologous stem cell transplantation receiving Melphelan therapy. Materials and Methods: The study was conducted in a prospective, randomized controlled study. Fifty patients who met the criteria for the study were recruited. Continuing to store the ice application in the intervention slots 5 minutes ago, continuing the treatment and spraying the next 15 minutes. continued throughout. Patients in the control devices received standard care. Results: It was found that the absence of oral mucositis in the intervention group was high at all times, the presence of mucositis in stage 2 was stable in both groups in all time periods, and the frequency of stage 3 mucositis was relatively higher in the control group from the 7th time period (p

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