DOI: 10.1039/d6tb00172f ISSN: 2050-750X
Melanocortin 1 receptor-targeted peptide-functionalized liposomes for enhanced melanocyte-preferential drug delivery and anti-melanogenic efficacy
Donghan Kim, Hwira Baek, Marta Gonçalves, Seyoung Yang, Seungjae Lee, Kyeongdeok Jang, Yun Ha Hwang, Jae Sung Hwang, Youngbok Lee, Jin Woong KimMC1R-targeted peptide-functionalized liposomes enable melanocyte-selective delivery via lipid raft endocytosis and macropinocytosis, achieving enhanced anti-melanogenic efficacy in reconstructed skin models for hyperpigmentation management.