DOI: 10.3390/pharmaceutics18080961 ISSN: 1999-4923
Mechanism-Based Pharmacokinetic and Pharmacodynamic Modeling
Artur ŚwierczekOver the past two decades, pharmacokinetic and pharmacodynamic (PK/PD) modeling has moved from the empirical fitting of concentration time and concentration effect data toward a mechanistic discipline that represents the biology connecting drug exposure to response [...]