Mapping the evolution and impact of microfluidic technology research on cancer diagnosis: A comprehensive bibliometric analysis from 2015 to 2024
Xinxiang Su, Junjun Pu, Jinxia Liao, Jilin Li, Juanjuan Huang, Zhen WuBackground:
To explore the research trends of microfluidic technology for cancer diagnosis from 2015 to 2024 using bibliometric and visualization methods (not a Preferred Reporting Items for Systematic Reviews and Meta-Analyses-compliant systematic review), and provide references for subsequent scientific research.
Methods:
Relevant literatures were retrieved from the Web of Science Core Collection, and analyzed using tools such as Origin 2018, R software, VOSviewer, and CiteSpace. The cooperation network, co - citation network, and keyword co - occurrence network was constructed.
Results:
A total of 897 literatures were included. The number of literatures first increased, then decreased, and then increased again, reaching a peak in 2023. China had the highest literature output (358 articles), but the international co - authorship rate was low (19%).
Conclusion:
This study clarified the research status and hotspots in this field. Microfluidic technology contributes to the early and accurate diagnosis of cancer. In the future, international cooperation should be strengthened to explore more potential of microfluidic technology in cancer diagnosis and improve the level of early diagnosis.