Lymphedema as a Significant Risk Factor for Primary Total Hip and Knee Arthroplasty Failure: A Systematic Review
Reza Zandi, Amir Mehrvar, Nima Keyhaninejad, Shakiba Shaterzadeh‐Bojd, Shahin Talebi, Elahe Foroughi, Faezeh Gouhari, Ahmadreza Ahmadi Abdashti, Akbar EhsaniABSTRACT
Background
Total hip and knee arthroplasty are highly effective for improving quality of life, alleviating pain, and enhancing physical function. However, failure of these joint replacements inflicts considerable burdens on patients and the healthcare system. The impact of lymphedema, as an uncommon comorbidity, in patients undergoing total hip and knee arthroplasties remains unknown. This study aimed to assess the most recent publications and evaluate the results and post‐operative complications of total joint arthroplasty in patients with preoperative lymphedema.
Methods
A systematic search of PubMed, Scopus, and Embase databases was conducted up to 25th October 2024 to identify relevant studies. Inclusion of studies was established through the application of a predetermined protocol by three independent reviewers. Joanna Briggs Institute (JBI) Critical Appraisal checklists were used for risk of bias assessment.
Results
Seven articles met the inclusion criteria. Five studies evaluated the outcomes of lymphedema in total knee arthroplasty, one in total hip arthroplasty, and one in total hip and knee arthroplasty. Lymphedema is a significant risk factor for postoperative complications in total hip and knee arthroplasty. The findings highlight the significance of patient optimization and enable improved lymphedema patient counseling.
Conclusion
Although lymphedema can be measured as a significant risk factor for complications in total hip and knee arthroplasty, further studies are required to investigate and confirm this relationship.