DOI: 10.1001/jamadermatol.2026.3103 ISSN: 2168-6068

Low-Concentration Topical Trametinib for Refractory Darier Disease

Diego Soto-García, María Susana Fortes Gónzalez, Susana Castro-Luaces, Catherine Tomé-Espiñeira, Cristian Sánchez-Espinel, África Gónzalez-Fernández, Ignacio García-Doval

This case report describes a woman in her 20s who presented with persistent, symptomatic truncal Darier disease and was treated with topical trametinib.

More from our Archive