Left Atrial Appendage Occlusion—Is the Case Now Closed?

doi:10.1001/jamaneurol.2026.3292

DOI: 10.1001/jamaneurol.2026.3292 ISSN: 2168-6149

Left Atrial Appendage Occlusion—Is the Case Now Closed?

David Seiffge, Richard A. Bernstein, Rod S. Passman, Charlotte Cordonnier

This Viewpoint disucsses how the results of CLOSURE-AF and CHAMPION-AF should inform decision-making regarding treatment with direct oral anticoagulants vs left atrial appendage closure for left atrial appendage occlusion.

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