DOI: 10.1039/d6fo04163a ISSN: 2042-6496

Layered glycoprotein nanoparticles co-delivering Meretrix meretrix -derived peptide and astaxanthin attenuate cyclophosphamide-induced immunosuppression

Wanyi Wu, Jiamin Cai, Zhixuan Wu, Wenhong Cao, Haisheng Lin, Jialong Gao, Xiuping Fan, Xiaoming Qin, Huina Zheng

Layered HA/yeast β-glucan-coated glycoprotein nanoparticles enabled oral co-delivery of MMIP and AST, with immune-related responses evaluated through intestinal distribution, macrophage uptake, gut microbiota-SCFAs, and splenic metabolomics.

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