DOI: 10.1093/chemle/upag166 ISSN: 0366-7022
Ir/NNSi-Potassium tert -Butoxide Catalyst System for C(sp3)–H Borylation Using Equimolar Amounts of Substrate and Bis(pinacolato)diboron
Takeru Torigoe, Tomoki Kawasaki, Toshimichi OhmuraAbstract
An Ir/NNSi-catalyzed alkyl C(sp3)–H borylation using equimolar amounts of substrate and bis(pinacolato)diboron is described. The performance of the Ir/NNSi catalyst was enhanced by the addition of a catalytic amount of KOtBu. Under these conditions, chemoselective C(sp3)–H borylation was achieved for a range of alkyl compounds, including THP-protected alkanols and ethylene glycol acetal-protected 5-nonanone.