DOI: 10.1039/d4ob00329b ISSN: 1477-0520

Iodomethane in C1 chemistry: application in palladium-catalyzed [2 + 2 + 1] annulation

Jin-Ke Zhang, Yu-Chen Fang, Jia-He Chen, Jing Shan, Mei Bai, Qiang Huang, Yong-Zheng Chen, Wen-Yong Han
  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

A variety of chromone-containing polycyclic compounds were smoothly forged in up to 93% yield via palladium-catalyzed [2 + 2 + 1] annulation of 3-iodochromones, bridged olefins, and iodomethane, in which iodomethane was used as the methylene source.

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