DOI: 10.1039/d6bm00920d ISSN: 2047-4830

Investigation of in vivo silk scaffold degradation by decoupling tissue ingrowth using a Gaussian process regression-driven digital twin framework

Guikang Wang, Xianying Chen, Shiwen Zheng, Yanjiu Li, Zhuowei Shen, Xiaohan Yu, Kun Shang, Jianliu Wang, Xiuli Sun, Di Jia

By using a Gaussian Process Regression-driven digital twin framework, we decouple  in vivo silk scaffold degradation from confounding tissue ingrowth, achieving a prediction of the bare scaffold's long-term structural fate in a non-adhered state.

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