DOI: 10.1039/d6ra07849d ISSN: 2046-2069
Insights into cytotoxic, metastasis-related effects and α-glucosidase inhibitory activities of the n -hexane extract and two isolated triterpenoids from Gymnosporia chevalieri
Nghia Ai Thi Doan, The-Huan Tran, Natsaranyatron Singharajkomron, Varisa Pongrakhananon, Chanon Loha, Krittapat Prachatimutte, Hien Minh Nguyen, Hanh Nhu Thi Hoang, Ty Viet Pham, Hoai Thi Nguyen, Linh Thuy Khanh Nguyen, Duc Viet HoGCL, GC3, and GC14 from G. chevalieri leaves reduced lung cancer cell migration and invasion. GCL and GC14 inhibited yeast α-glucosidase. Exploratory in silico analyses examined predicted protein–ligand interactions.