DOI: 10.1039/d6qo00816j ISSN: 2052-4129
Indole nitrogen-directed Petasis-type allylation of dihydro-β-carbolinium ions enables concise total syntheses of indole alkaloids
Kai Cheng, Jialong Li, Mingming Gong, Yankun Liu, Jianyi Wang, Rongbiao Tong, Lixin LiangHerein, we report an indole nitrogen-directed Petasis-type allylation for preparing versatile C1-allyl tetrahydro-β-carbolines. The synthetic utility of this method has been demonstrated with concise total synthesis of three indole alkaloids.