DOI: 10.4103/ghep.ghep_23_23 ISSN: 2772-2732
Indian Literature Review on Nonalcoholic Fatty Liver Disease
Balamurali Rangachari, Manimaran Murugesan, Chitra Shanmugam, Sathya Gopalsamy, Krishna Kumar Chinnadurai- General Medicine
Abstract
Nonalcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease worldwide. The global prevalence of NAFLD has increased from 25.3% in 1990–2006 – 38.0% in 2016–2019. Easy access to calorie-dense food and a sedentary lifestyle together with the modern epidemics of diabetes mellitus and obesity have catapulted NAFLD into a substantial public health problem in India as in other parts of the world. NAFLD has emerged as one of the leading causes of hepatocellular carcinoma and liver transplant in India. In this review, we summarized the Indian perspective of NAFLD epidemiology, risk factors, assessment, spectrum, lifestyle interventions, treatment options, and transplant prospects.