DOI: 10.1148/rycan.250758 ISSN: 2638-616X

Incremental Value of Synthetic MRI Radiomics in Predicting Neoadjuvant Response in Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer

Siyi Chen, Yongxin Chen, Chen Jin, Bingjie Zheng, Shishen Ding, Zijin Weng, Wenjie Tang, Weifeng Liu, Yihong Lin, Qingcong Kong, Qianwei Zhou, Yuan Guo

Synthetic MRI radiomics accurately predicted pathologic complete response to neoadjuvant therapy in human epidermal growth factor receptor 2–positive breast cancer, outperformed traditional radiomics models, and was associated with immune-related pathways and recurrence-free survival.

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