DOI: 10.1039/d6lc00633g ISSN: 1473-0197

Improving CTC isolation by controlling orbit engagement in inertial microfluidics

Chiara F. Ghera, Roslyn Hay, Jian Zhou, Benjamin Owen, Ian Papautsky

Flow split control promotes earlier heteroclinic orbit engagement, stabilizing inertial migration and improving target cell routing. Validation included CTC scale particles, tumor cell lines, and an IPMN patient sample.