IMPROVED SYNTHESIS OF UNSYMMETRICAL UREAS VIA N-ALKYL CARBAMATES

An efficient, cost-effective, easy and green method is reported for the preparation of N,N’-alkyl aryl ureas and N,N’-dialkylureas via carbamates. This improved procedure is devoid of any hazardous reagents such as phosgent, isocyanates etc. and has shown a broad substrate scope with good to excellent yields. As compared to literature reports, this procedure is operationally simple, potentially scalable and significantly benign to synthesize these important motifs.