Immune-instructive baicalin-loaded nanofibrous membranes regulate macrophage polarization
                    <i>via</i>
                    PI3K/AKT/GSK3β signaling for enhanced cutaneous wound healing

doi:10.1039/d6tb01099g

DOI: 10.1039/d6tb01099g ISSN: 2050-750X

Immune-instructive baicalin-loaded nanofibrous membranes regulate macrophage polarization via PI3K/AKT/GSK3β signaling for enhanced cutaneous wound healing

Keting Liu, Fuying Chen, Hanzheng Kuang, Yumei Xiao, Xiao Yang, Xiangfeng Li, Xuening Chen, Xiangdong Zhu

Sustained baicalin release from mesoporous silica nanoparticles (MSNs) promotes macrophage M2 polarization via PI3K/AKT/GSK3β signaling, creating an immune-instructive microenvironment for enhanced cutaneous wound healing.

Outline

Immune-instructive baicalin-loaded nanofibrous membranes regulate macrophage polarization via PI3K/AKT/GSK3β signaling for enhanced cutaneous wound healing

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