Immediate Krukenberg Procedure in a Dystrophic Epidermolysis Bullosa Patient with Advanced Squamous Cell Carcinoma of the Hand – A Case Report

Epidermolysis bullosa (EB) results in blistering of the skin and impaired wound healing. These factors increase the risk of developing cutaneous squamous cell carcinoma (cSCC), which may require amputation. Reconstructive options post upper limb amputation are limited in patients with EB, for reasons discussed below. We present a case report of one such patient with advanced cSCC of the hand who underwent a distal forearm amputation followed by a primary Krukenberg procedure. This patient had already undergone a contralateral forearm amputation for the same reason. The patient had an uneventful post-operative recovery and regained full independence in basic activities of daily living. In conclusion, the Krukenberg procedure can be considered as a reconstructive option in cases of severe EB with locally advanced cSCC requiring hand amputation.

Level of Evidence: Level V (Therapeutic)