DOI: 10.1039/d6sc03993f ISSN: 2041-6520

In situ glycosylation-directed H-aggregation of Type I photosensitizers for synergistic biofilm eradication and promoting diabetic wound healing

Dongmei Xi, Wencai Jiang, Mengyue Li, Jialu Guo, Pengxiang Wang, Fangqian Yin, Xiaopeng Fan, Ke-Rang Wang, Wen Sun, Xiaojun Peng

Glycosylated NBS-Lac forms H-aggregates to enhance charge transfer and ISC, boosting O 2 ˙ production. This hypoxia-active photosensitizer achieves potent antibiofilm activity and accelerates diabetic wound healing with excellent biosafety.

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