DOI: 10.1093/cid/ciad476 ISSN:
Identifying Effective Durations of Antibiotic Therapy for the Treatment of Carbapenem-resistant Enterobacterales Bloodstream Infections: A Multicenter Observational Study
Caitlin L Soto, Alice J Hsu, Jae Hyoung Lee, Kathryn Dzintars, Rebecca Choudhury, Timothy C Jenkins, Erin K McCreary, Katelyn S Quartuccio, Erica J Stohs, Matty Zimmerman, Pranita D Tamma- Infectious Diseases
- Microbiology (medical)
Abstract
In a propensity-score-weighted cohort of 183 adults with carbapenem-resistant Enterobacterales bacteremia at 24 United States hospitals, patients receiving short-courses of active therapy (7-10 days, median 9 days) experienced similar odds of recurrent bacteremia or death within 30 days as those receiving prolonged courses of active therapy (14-21 days, median 14 days).