ID #631 Promoting Resilience in Stress Management (PRISM): The feasibility of integrating PRISM within a pediatric neuro-oncology population
Jessica Feinstein, Erin Wright, Alexis Judd, Joyce Yi-Frazier, Kaylyn JonesAbstract
Background
Psychological late effects, including anxiety and depression, are a long-term consequence within the pediatric neuro-oncology population. Resilience has been found to protect against symptoms of stress and depression in adolescence. PRISM is a brief evidence-based coaching program, found to improve patient-reported resilience, quality of life, and distress. The project evaluated the feasibility of integrating PRISM for adolescent patients within a Pediatric Neuro-Oncology service.
Method
Feasibility was measured in two ways: 1) >50% of adolescent patients being offered PRISM, and 2) >70% of participants completing the PRISM intervention. Participants were identified via a neuro-oncology patient database. Patients met eligibility criteria if they were ages 12-25, cognitively able to participate, proficient in English, and actively on treatment or within 2 years of initial or recurrent brain tumor diagnosis.
Results
65 patients were identified: 41 patients were not eligible, primarily due to age (N = 28). Of the remaining 24 patients, 6 patients enrolled, 5 patients declined participation, and 13 patients did not respond. Of the patients who enrolled in PRISM, 2 patients successfully completed the PRISM intervention, 1 patient requested a break due to current medical treatment complications, and 2 patients are on the waitlist to receive the intervention. Preliminary baseline results found that each participant scored below average on a measure of resilience. Additionally, 3 patients displayed moderate to severe symptoms of anxiety and impaired functioning across quality-of-life domains.
Conclusions
Based on the preliminary findings, integrating PRISM as a standard of care for adolescent patients was found to be feasibile (>50% of adolescent patients being offered PRISM and hypothesized >70% of participants completing the PRISM intervention). Questionnaires identified symptoms and impaired functioning. Longitudinal data will be collected to measure efficacy of the intervention including patient-reported resilience, mood, and quality of life 6- and 9-months following PRISM completion.
1. Shin, H., Dudley, W. N., Bhakta, N., Horan, M. R., Wang, Z., Bartlett, T. R., Srivastava, D., Yasui, Y., Baker, J. N., Robison, L. L., Ness, K. K., Krull, K. R., Hudson, M. M., & Huang, I. C. (2023). Associations of symptom clusters and health outcomes in adult survivors of childhood cancer: A report from the St Jude Lifetime Cohort Study. Journal of Clinical Oncology, 41(3), 497–507. https://doi.org/10.1200/JCO.22.00361
2. Lau W. K. W. (2022). The role of resilience in depression and anxiety symptoms: A three-wave cross-lagged study. Stress & Health, 38(4), 804–812. https://doi.org/10.1002/smi.3136