Ibrutinib-loaded potato starch nanoparticles conjugated with melatonin for colorectal cancer therapy:
                    <i>in silico</i>
                    and
                    <i>in vitro</i>
                    evaluation of therapeutic poten

doi:10.1039/d6pm00474a

DOI: 10.1039/d6pm00474a ISSN: 2976-8713

Ibrutinib-loaded potato starch nanoparticles conjugated with melatonin for colorectal cancer therapy: in silico and in vitro evaluation of therapeutic poten

Yash Dhananand Sonawane, Sankha Bhattacharya

In HT-29 colorectal cancer cells, melatonin-conjugated potato starch nanoparticles of ibrutinib facilitate pH and enzyme-responsive ibrutinib administration, improving cellular uptake and death while lowering inflammatory cytokines.

Outline

Ibrutinib-loaded potato starch nanoparticles conjugated with melatonin for colorectal cancer therapy: in silico and in vitro evaluation of therapeutic poten

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