DOI: 10.1039/d6tb01306f ISSN: 2050-750X

Hyaluronic acid–alginate hydrazone crosslinked hydrogels support the generation and maturation of V2a interneurons

Alycia N. Galindo, Madison E. McLaren, Alyssa K. Chi, Jenna D. Khachatourian, Jessica C. Butts, Marian H. Hettiaratchi

Hyaluronic acid and alginate hydrogels were functionalized with ECM-derived peptides (RGD/IKVAV) and crosslinked via hydrazone crosslinking to support 3D embedding of mouse embryonic stem cells and their differentiation into V2a interneurons.