Histomorphological Overview of Central Nervous System Tumors at a Tertiary Care Center
Shruti Gajanan Umale, Ashish Tayde, Chetna Agrawal, R. R. Soni
A
BSTRACT
Introduction:
Central nervous system (CNS) tumors are rare and constitute about 1%–2% of all malignancies with high morbidity and mortality. Different types of CNS tumors vary in their location within the CNS in age and gender distribution, growth potential, extent of invasiveness, morphological features, tendency for progression, and clinical course.
Materials and Methods:
In 12 months of a cross-sectional study at a tertiary care center, a total of 40 CNS neoplasms were received, and sections were processed by routine paraffin techniques and stained using hematoxylin and eosin.
Results:
During the study period, the most predominant age group affected was 35–65 years. In this study, CNS tumors showed female predominance. Out of 40 cases, 38 were primary CNS tumors and 2 were metastatic. Meningiomas were most commonly found.
Conclusion:
Irrespective of advanced techniques, histopathological examination is the gold standard in diagnosing and classifying CNS tumors. An accurate diagnosis is possible after careful assessment of histomorphological features and clinical and radiological findings.