DOI: 10.1039/d6tb01429a ISSN: 2050-750X
Hierarchical embolization integrating hypoxia modulation and immune reprogramming for enhanced hepatocellular carcinoma therapy
Chuyue Zhang, Han Wu, Enyun Xing, Jianing Shi, Mohamed F. Mady, Xiaomin Li, Tian Yang, Lijun ShiA hierarchical embolic strategy based on mSiO 2 /Pt/aPD-1@HAMA microspheres is designed to promote vascular occlusion, relieve tumor hypoxia, and improve anti-PD-1 immunotherapy for hepatocellular carcinoma.