DOI: 10.1177/09603271261478448 ISSN: 0960-3271
Hemodialysis in severe lactic acidosis with concurrent ethanol intoxication
Chi-Syuan Pan, Dong-Zong Hung, Han-Wei Mu, Chun-Hung Chen, Kai-Wei Yang, Jiun-Hao YuPurpose
To identify clinical markers associated with hemodialysis in patients with severe lactic acidosis and concurrent ethanol intoxication.
Methods
A retrospective study of 22 adults (pH < 7.20, lactate > 5.0 mmol/L). We compared hemodialyzed (n=6) and non-hemodialyzed (n=16) patients.
Results
Hemodialysis was associated with higher peak lactate (24.4 vs 13.7 mmol/L), lower lactate clearance (4.5% vs 7.9%/h), and more profound acidemia (pH 6.7 vs 6.94). Vasopressor use was exclusive to the hemodialysis group.
Conclusion
Hemodialysis may serves as a physiological rescue therapy for metabolic collapse in this population.