DOI: 10.1039/d6sc03923e ISSN: 2041-6520
Guiding point-of-care therapeutic drug monitoring through structure–toxicity principles
Jiarui Wang, Lingling Guo, Chuanlai Xu, Aihua Qu, Hua Kuang, Xinxin XuA structure–toxicity strategy was employed to generate monoclonal antibodies exhibiting a gradient of affinity corresponding to the toxicity level of biguanides, and an immunochromatographic sensor was established for diabetes drug risk monitoring.