Guidance on the Ethical Use of Mandates for Vaccination Prior to Organ Transplantation in Children: An Analysis From the
IPTA
Ethics Committee
M. Damian, M. A. Freeman, S. Rao, A. Wightman, T. Blydt‐Hansen, ABSTRACT
Background
IPTA is a multidisciplinary international professional organization composed of pediatric transplant experts who aim to improve the health of all children with end‐stage organ failure by advancing the science and practice of pediatric transplantation worldwide. The IPTA Ethics committee seeks to provide guidance on ethical issues pertaining to pediatric transplantation in a global context. There is broad consensus that pre‐transplant vaccination decreases the risk of many preventable diseases and the IPTA leadership, committees, and membership unequivocally support immunizations for all children. However, the use of mandated vaccination as criteria for transplant eligibility in the under‐vaccinated pediatric population remains ethically complex.
Methods
In this guidance document, we explore ethical arguments for and against the use of mandated vaccination as a requirement for transplant eligibility.
Results
Considerations in this ethical analysis included assessments of the potential benefits and/or harms experienced by potential recipients for whom vaccination may be required, concerns for appropriate respect for and the limits of parental authority, and societal considerations including organ stewardship, the social contract implicit in organ allocation practices, broader considerations of population safety, and disparities in opportunities for transplant.
Conclusion
This analysis is designed to support clinicians, transplant programs, and, where applicable, regional and national policy makers in evaluating the ethical justifiability of pre‐transplant vaccination requirements for pediatric solid organ transplant candidates. It does not prescribe a single policy approach for all settings but rather offers a structured ethical framework and consensus statements to inform local, regional, and national deliberation.