DOI: 10.1093/bjd/ljag332 ISSN: 0007-0963
Giant Angiokeratoma Circumscriptum Naeviforme
Adam Aizek Grempel, Wael Zaina, Tomer Cohen, Michael Ziv, Eran Cohen-BarakWe report an 18-year-old male with a 20 cm angiokeratoma circumscriptum naeviforme, the largest case on record among fewer than 50 reported worldwide. As standard treatments proved insufficient, topical sirolimus was initiated, highlighting mTOR inhibition as a potential therapeutic avenue for this exceptionally rare vascular anomaly.