Outline
DOI: 10.1039/d6np00052e ISSN: 0265-0568
Genomic scale analysis of assembly-line polyketide synthase diversity and evolution
Seokyoung Lee, Chaitan KhoslaPKSClusterDB provides a curated genomic-scale catalogue of assembly-line PKSs, enabling anchor-window analysis that reveals family-resolved evolutionary patterns and helps interpret orphan pathways and biosynthetic diversity.
More from our Archive
- DOI: 10.1242/jeb.252227 2026When repair mechanisms fail to keep up: high UVB irradiance causes disproportionate accumulation of DNA lesionsNiclas U. Lundsgaard, Craig E. Franklin, Rebecca L. Cramp
- DOI: 10.1177/23996544261466050 2026Writing against erasure: A geography of resistance in GazaLubna Ahmad Abu Sitta
- DOI: 10.1148/rg.250085 2026Early Pancreatic Cancer: Clinical Implications, Workup, and Imaging Findings with Histopathologic Correlation for Personalized SurveillanceShintaro Kano, Wataru Gonoi, Moto Nakaya, Shohei Inui, Yudai Nakai, Sota Masuoka, Tomohiko Masumoto, Manabu Minami, Ayman H. Gaballah, Osamu Abe
- DOI: 10.1017/pds.2026.10666 2026Challenges in understanding, using, and teaching design methods: perspectives of design educatorsMayank Mayookh, V. Srinivasan
- DOI: 10.1136/bmj-2026-100016 2026Venous thromboembolism after mechanical restraint in psychiatric hospitals: population based cohort and self-controlled case series studyJakob Hansen Viuff, Lars Pedersen, Irene Petersen, Jan P Vandenbroucke, Søren Dinesen Østergaard, Henrik Toft Sørensen
- DOI: 10.1097/olq.0000000000002356 2026The Potential for Combined Treponemal/Nontreponemal Rapid Point-of-Care Test and Treponema pallidum Polymerase Chain Reaction in the Diagnosis of Gestational and Congenital Syphilis in a Low-Resource, High-Prevalence Setting: Pilot Data From MalawiDeirdre J Foley, Vita Nyasulu, Chifundo Kondoni, Annie Kuyere, Fatima Mtonga, George Shaba, James Jafali, Chelsea Morroni, Michael Marks, Patrick Mallon, David Lissauer, Gladys Gadama, Luis Gadama, Kondwani Kawaza, Charlotte van der Veer, Bridget Freyne
- DOI: 10.1097/olq.0000000000002347 2026Advancements in Syphilis Vaccine DevelopmentLorenzo Giacani, Caroline E. Cameron, Feijun Zhao, Melissa J. Caimano, Justin D. Radolf
- DOI: 10.1097/olq.0000000000002353 2026Evaluation of Partner Notification Strategies to Improve Syphilis Management in Pregnancy in Blantyre, Malawi: A Mixed-Methods StudyKondwani Kaitume Kaunda, Deirdre J. Foley, Michael Marks, Annielisa Majamanda, Monica Patricia Malata, Catherine Bamuya, Chifundo Kondoni, Gladys Membe Gadama, David Lissauer, Chelsea Morroni, Peter MacPherson, Effie Chipeta, Linda Mipando, Brynne Gilmore, Bridget Freyne
- DOI: 10.1097/olq.0000000000002331 2026Potential Strategies for Participation and Community Engagement in Syphilis Clinical ResearchMitch M. Matoga, Suzanne Day, Dan Wu, Zhuoheng Yin, Bolin Cao, Zou Huachun, Barbara Van Der Pol, Joseph D. Tucker
- DOI: 10.1097/olq.0000000000002349 2026Key Considerations in Evaluating Syphilis TherapeuticsLisa Frigati, Laurens Manning, Michael Marks, Oriol Mitjà, Thomas Fitzpatrick, Pingyu Zhou