DOI: 10.3390/jcdd10120495 ISSN: 2308-3425

Genetics in Ischemic Stroke: Current Perspectives and Future Directions

Ka Zhang, Shaun Loong, Linus Yuen, Narayanaswamy Venketasubramanian, Hui-Lin Chin, Poh Lai, Benjamin Tan
  • Pharmacology (medical)
  • General Pharmacology, Toxicology and Pharmaceutics

Ischemic stroke is a heterogeneous condition influenced by a combination of genetic and environmental factors. Recent advancements have explored genetics in relation to various aspects of ischemic stroke, including the alteration of individual stroke occurrence risk, modulation of treatment response, and effectiveness of post-stroke functional recovery. This article aims to review the recent findings from genetic studies related to various clinical and molecular aspects of ischemic stroke. The potential clinical applications of these genetic insights in stratifying stroke risk, guiding personalized therapy, and identifying new therapeutic targets are discussed herein.

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