DOI: 10.1200/go-26-00222 ISSN: 2687-8941

Generative Artificial Intelligence Use, Perceptions, and Expectations Among Argentine Oncology Health Care Professionals: A Cross-Sectional Survey

Federico Losco, Andrea Marchioni, Enrique A. Diaz-Canton, José M. Barros, Diego H. Enrico, Pablo E. Companys, Martin Angel, Román Oberti, Carlos R. Picón

Purpose

To describe perceptions and use regarding generative artificial intelligence (GAI) among oncology professionals across two surveys at the Argentine Association of Clinical Oncology (AAOC) meetings (2024-2025).

Methods

Two independent cross-sectional surveys were administered on-site using an expert-consensus instrument, assessing demographics, GAI use, frequency, trust, perceived impact, training needs, and barriers. Categorical data are reported as frequencies and percentages with Wilson 95% CIs; between-year comparisons used Fisher's exact test (exploratory).

Results

A total of 268 valid responses were analyzed (2024: n = 164; 2025: n = 104); 48.1% of respondents were male, 35.4% were age 36-45 years, and 40.7% had 10-20 years of experience. GAI use in the previous month was 69.0% (95% CI, 63.3 to 74.3) overall, 61.0% (95% CI, 53.3 to 68.1) in 2024 and 80.8% (95% CI, 72.2 to 87.2) in 2025. Near-daily use rose from 12.2% (95% CI, 8.0 to 18.1) to 33.7% (95% CI, 25.3 to 43.2) and was more frequent among younger participants ( P = .048; P = .009). Main applications include administrative tasks (54.9%), scientific retrieval (41.8%), clinical consultation (15.3%), and patient information (7.1%). Most (79.1%, 95% CI, 73.8 to 83.5) had no formal GAI training; 92.9% (95% CI, 89.2 to 95.4) considered it necessary and 82.5% (95% CI, 77.5 to 86.5) believed GAI can improve cancer care. Trust in AI recommendations was higher in 2025 (67.3%, 95% CI, 57.8 to 75.6) than in 2024 (51.8%, 95% CI, 44.2 to 59.3). Privacy concerns (87.3%, 95% CI, 82.8 to 90.8), legal liability (70.1%), and support for regulation (84.0%, 95% CI, 79.1 to 87.9) were widespread.

Conclusion

GAI use was high and increasing, occurring without institutional support or formal training. These findings support educational program development and context-appropriate guidance for responsible adoption. To our knowledge, this is the first study characterizing GAI perception and use among oncology professionals in Argentina.