From imaging to insight: Assessing the diagnostic performance of MRI in endometrial cancer staging
Deeksha Sharma, Lajya D. Goyal, Parveen Rajora, Paramdeep Singh, Khushpreet KaurABSTRACT
Background:
Endometrial carcinoma (EC), one of the most common malignancies of the female reproductive tract, predominantly affects postmenopausal women. The incidence of EC has been rising over the past few decades, partly due to increasing rates of obesity, diabetes, and an aging population. A variety of diagnostic techniques exist to assess and diagnose endometrial carcinoma, including histopathology and imaging modalities such as ultrasonography, computed tomography (CT), and magnetic resonance imaging (MRI). MRI can provide valuable information about the anatomical characteristics of the tumor, such as the depth of myometrial invasion, cervical involvement, and the presence of lymph node or distant metastases, which can help guide treatment decisions.
Material and Methods:
A total of 50 biopsy proven cases of endometrial carcinoma were enrolled in the study and subjected to MRI. After the staging laparotomy, the comparison of preoperative MRI with histopathological findings was done.
Results:
MRI showed a very good correlation with HPE for all the 3 parameters with accuracy of 90% for myometrial invasion, 72% for cervical involvement, and 90% for lymph node metastasis.
Conclusion:
MRI provides excellent soft tissue contrast and detailed visualization. MRI’s noninvasive nature and high sensitivity makes it an invaluable diagnostic tool for preoperative staging, guiding clinical decision-making and treatment planning.