DOI: 10.1039/d6cs00041j ISSN: 0306-0012
From Fenton reaction to ferroptosis: chemistry of metal complexes in regulated cell death by lipid peroxidation
S. Shivangi, Bidare N. SharathBabu, Govindasamy MugeshMetal complexes are potent triggers of ferroptosis, an iron-dependent oxidative cell death, as their redox activity and tunable ligand frameworks enable selective disruption of antioxidant defenses for next-generation anticancer therapies.