From Chlorophyll to Micro Biome: Wheatgrass’s Role in Gut Health—A Comprehensive Review
Rashmitha Alva, Deeksha Shenoy, Vanitha ShettyAbstract
Background:
Wheatgrass (
Objective:
This review aims to critically evaluate the existing scientific evidence on the effects of wheatgrass consumption on gut health, with particular emphasis on its potential influence on gut microbiota composition, function, and gut-related health outcomes.
Methods:
A comprehensive literature search was conducted using PubMed, Scopus, and other scientific databases up to June 2025. Studies assessing wheatgrass intake in relation to gastrointestinal health, inflammatory biomarkers, or microbiota-related outcomes were included.
Results:
No human or animal intervention studies directly examining the effects of wheatgrass on gut microbiome composition were identified. However, mechanistic, and phytochemical studies suggest that wheatgrass-derived polysaccharides and phenolic compounds may support gut health through prebiotic, antioxidant, and immunomodulatory mechanisms. Available clinical and preclinical evidence indicates that wheatgrass supplementation may reduce gastrointestinal inflammation, enhance mucosal integrity, and promote the growth of beneficial gut microorganisms.
Conclusion:
Wheatgrass is a nutritionally rich functional food with potential gut health benefits; however, direct evidence linking wheatgrass consumption to changes in gut microbiome composition and function is limited. Well-designed animal and clinical studies are needed to clarify its effects on gut microbiota diversity, short-chain fatty acid production, and overall gastrointestinal health.