DOI: 10.18609/bci.2026.028 ISSN: 2977-8301

From bench to bedside: translating novel-target ADCs against treatment-resistant tumors

Valerie Vanhooren

Lauren Coyle, Launch Commissioning Editor, Bioconjugate Insights, speaks with Valerie Vanhooren, Co-Founder and CEO, Ona Therapeutics, about translating first-in-class ADCs from bench to bedside, including target validation, resistance biology, linker-payload strategy, and the company culture that sustains high-risk, high-gain drug development.